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Anti-phospho-ESR1 (Tyr537) Monoclonal Antibody (6J710)

(Synonyms: NR3A1, ESTRR, ESRA, ESR, Era, ER) Copy Product Info
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Synonyms: NR3A1, ESTRR, ESRA, ESR, Era, ER

Catalog No. TMAT-0674 Copy Product Info
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Anti-phospho-ESR1 (Tyr537) Monoclonal Antibody (6J710) is a Mouse antibody targeting phospho-ESR1 (Tyr537). Anti-phospho-ESR1 (Tyr537) Monoclonal Antibody (6J710) can be used in FCM.

Anti-phospho-ESR1
(Tyr537) Monoclonal Antibody
(6J710)

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Product Introduction

Bioactivity
Description
Anti-phospho-ESR1 (Tyr537) Monoclonal Antibody (6J710) is a Mouse antibody targeting phospho-ESR1 (Tyr537). Anti-phospho-ESR1 (Tyr537) Monoclonal Antibody (6J710) can be used in FCM.
SynonymsNR3A1, ESTRR, ESRA, ESR, Era, ER
Ig Type
IgG1
Clone
6J710
Reactivity
Human
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Synthesized peptide of human Eralpha(AA: 530-542 (Tyr-537)) expressed in E. Coli.
Antigen Species
Human
Gene Name
ESR1
Gene ID
Protein Name
Estrogen receptor
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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