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Anti-PHB Monoclonal Antibody (8H388)
(Synonyms: PHB1) Copy Product Info
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Synonyms: PHB1
Catalog No. TMAT-0988 Copy Product Info
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Anti-PHB Monoclonal Antibody (8H388) is a Mouse antibody targeting PHB. Anti-PHB Monoclonal Antibody (8H388) can be used in WB,IHC,IF,FCM.
Anti-PHB Monoclonal Antibody
(8H388)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-PHB Monoclonal Antibody (8H388) is a Mouse antibody targeting PHB. Anti-PHB Monoclonal Antibody (8H388) can be used in WB,IHC,IF,FCM. |
| Synonyms | PHB1 |
| Ig Type | IgG1 |
| Clone | 8H388 |
| Reactivity | Human,Mouse,Rat,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PHB expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PHB1 |
| Gene ID | |
| Protein Name | Prohibitin 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 30 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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