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Anti-PGA5 Monoclonal Antibody (5Q959)
(Synonyms: Pepsinogen 5, Pepsin A) Copy Product Info
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Synonyms: Pepsinogen 5, Pepsin A
Catalog No. TMAT-0788 Copy Product Info
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Anti-PGA5 Monoclonal Antibody (5Q959) is a Mouse antibody targeting PGA5. Anti-PGA5 Monoclonal Antibody (5Q959) can be used in WB,IHC.
Anti-PGA5 Monoclonal Antibody
(5Q959)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-PGA5 Monoclonal Antibody (5Q959) is a Mouse antibody targeting PGA5. Anti-PGA5 Monoclonal Antibody (5Q959) can be used in WB,IHC. |
| Synonyms | Pepsinogen 5, Pepsin A |
| Ig Type | IgG1 |
| Clone | 5Q959 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PGA5 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PGA5 |
| Gene ID | |
| Protein Name | Pepsin A-5 |
| Uniprot ID |
| Molecular Weight | Theoretical: 42 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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