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Synonyms: STF-1, PDX-1, MODY4, IUF1, IPF1, IDX-1, GSF
Anti-PDX1 Monoclonal Antibody
(2L263)

| Description | Anti-PDX1 Monoclonal Antibody (2L263) is a Mouse antibody targeting PDX1. Anti-PDX1 Monoclonal Antibody (2L263) can be used in FCM. |
| Synonyms | STF-1, PDX-1, MODY4, IUF1, IPF1, IDX-1, GSF |
| Ig Type | IgG1 |
| Clone | 2L263 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PDX1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PDX1 |
| Gene ID | |
| Protein Name | Pancreas/duodenum homeobox protein 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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