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Anti-PDHA1 Monoclonal Antibody (6P315)
(Synonyms: PHE1A, PDHCE1A, PDHAD, PDHA) Copy Product Info
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Synonyms: PHE1A, PDHCE1A, PDHAD, PDHA
Catalog No. TMAT-0761 Copy Product Info
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Anti-PDHA1 Monoclonal Antibody (6P315) is a Mouse antibody targeting PDHA1. Anti-PDHA1 Monoclonal Antibody (6P315) can be used in WB,IP,IHC,IF,FCM.
Anti-PDHA1 Monoclonal Antibody
(6P315)
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| Description | Anti-PDHA1 Monoclonal Antibody (6P315) is a Mouse antibody targeting PDHA1. Anti-PDHA1 Monoclonal Antibody (6P315) can be used in WB,IP,IHC,IF,FCM. |
| Synonyms | PHE1A, PDHCE1A, PDHAD, PDHA |
| Ig Type | IgG1 |
| Clone | 6P315 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IP: 1/200-1/300; IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PDHA1(AA: 241-390) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PDHA1 |
| Gene ID | |
| Protein Name | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial |
| Uniprot ID |
| Molecular Weight | Theoretical: 43 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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