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Anti-Pan Cytokeratin Antibody (7X356) (ready to use)

Catalog No. TMAB-09956 Copy Product Info
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Anti-Pan Cytokeratin Antibody (7X356) is a Mouse antibody targeting Pan Cytokeratin. Anti-Pan Cytokeratin Antibody (7X356) can be used in IHC-P,IHC-Fr,IF.

Anti-Pan Cytokeratin Antibody (7X356) (ready to use)

Copy Product Info
🥰Excellent
Catalog No. TMAB-09956

Anti-Pan Cytokeratin Antibody (7X356) is a Mouse antibody targeting Pan Cytokeratin. Anti-Pan Cytokeratin Antibody (7X356) can be used in IHC-P,IHC-Fr,IF.

Anti-Pan Cytokeratin Antibody
(7X356)
(ready to use)
Pack SizePriceUSA StockGlobal StockQuantity
3 mL$1027-10 days7-10 days
6 mL$1857-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Pan Cytokeratin Antibody (7X356) is a Mouse antibody targeting Pan Cytokeratin. Anti-Pan Cytokeratin Antibody (7X356) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG2b
Clone
7X356
Reactivity
Human
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (human cervical carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Pan Cytokeratin) Monoclonal Antibody, Unconjugated (TMAB-09956) overnight at 4°C, followed by operating according to SP Kit (Mouse) instructions and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded (human gastric carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Pan Cytokeratin) Monoclonal Antibody, Unconjugated (TMAB-09956) overnight at 4°C, followed by operating according to SP Kit (Mouse) instructions and DAB staining.
Application
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCytoplasmic.
Tissue Specificityepithelial cells
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300.
Research BackgroundCytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Pan Cytokeratin
Antigen Species
Human
Gene Name
KRT24
Gene ID
Protein Name
Keratin, type I cytoskeletal 24
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 42-64 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze.
TransportShipping with blue ice.

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