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Anti-Pan Cytokeratin Antibody (7X356) is a Mouse antibody targeting Pan Cytokeratin. Anti-Pan Cytokeratin Antibody (7X356) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 3 mL | $102 | 7-10 days | 7-10 days | |
| 6 mL | $185 | 7-10 days | 7-10 days |
| Description | Anti-Pan Cytokeratin Antibody (7X356) is a Mouse antibody targeting Pan Cytokeratin. Anti-Pan Cytokeratin Antibody (7X356) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG2b |
| Clone | 7X356 |
| Reactivity | Human |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasmic. |
| Tissue Specificity | epithelial cells |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300. |
| Research Background | Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection. |
| Immunogen | KLH conjugated synthetic peptide: human Pan Cytokeratin |
| Antigen Species | Human |
| Gene Name | KRT24 |
| Gene ID | |
| Protein Name | Keratin, type I cytoskeletal 24 |
| Uniprot ID |
| Molecular Weight | Theoretical: 42-64 kDa. |
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
| Transport | Shipping with blue ice. |
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