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Anti-OSMR Antibody (3Z636) (Synonyms: OSMRB, oncostatin M receptor)

Catalog No. TMAY-03327 Copy Product Info
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Anti-OSMR Antibody (3Z636) is a Rabbit antibody targeting OSMR. Anti-OSMR Antibody (3Z636) can be used in ELISA.

Anti-OSMR Antibody (3Z636)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03327
Synonyms OSMRB, oncostatin M receptor

Anti-OSMR Antibody (3Z636) is a Rabbit antibody targeting OSMR. Anti-OSMR Antibody (3Z636) can be used in ELISA.

Anti-OSMR Antibody
(3Z636)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-OSMR Antibody (3Z636) is a Rabbit antibody targeting OSMR. Anti-OSMR Antibody (3Z636) can be used in ELISA.
SynonymsOSMRB, oncostatin M receptor
Ig Type
Rabbit IgG
Clone
3Z636
Reactivity
Mouse
Specificity
Mouse OSMR
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse OSMR / IL-31RB (rM OSMR / IL-31RB; TMPY-02335; O70458-1; Met1-Leu738).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundOncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the type I cytokine receptor family. IL-31RB/OSMR heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in IL-31RB/OSMR have been associated with familial primary localized cutaneous amyloidosis. Defects in IL-31RB/OSMR are the cause of amyloidosis primary localized cutaneous type 1 (PLCA1), also known as familial lichen amyloidosis of familial cutaneous lichen amyloidosis. PLCA1 is hereditary primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening (lichenification) that may be exacerbated by chronic scratching and rubbing. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse OSMR / IL-31RB Protein (TMPY-02335)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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