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Synonyms: RACK17, PRKCBP2, OLIGO2, OLIG2, bHLHe19, BHLHB1
Anti-OLIG2 Monoclonal Antibody
(8M779)

| Description | Anti-OLIG2 Monoclonal Antibody (8M779) is a Mouse antibody targeting OLIG2. Anti-OLIG2 Monoclonal Antibody (8M779) can be used in IHC,IF. |
| Synonyms | RACK17, PRKCBP2, OLIGO2, OLIG2, bHLHe19, BHLHB1 |
| Ig Type | IgG1 |
| Clone | 8M779 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human OLIG2 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | OLIG2 |
| Gene ID | |
| Protein Name | Oligodendrocyte transcription factor 2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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