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Anti-NTRK3 Monoclonal Antibody (5D775)
(Synonyms: TRKC, gp145(trkC)) Copy Product Info
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Synonyms: TRKC, gp145(trkC)
Catalog No. TMAT-1357 Copy Product Info
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Anti-NTRK3 Monoclonal Antibody (5D775) is a Mouse antibody targeting NTRK3. Anti-NTRK3 Monoclonal Antibody (5D775) can be used in IHC.
Anti-NTRK3 Monoclonal Antibody
(5D775)
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| Description | Anti-NTRK3 Monoclonal Antibody (5D775) is a Mouse antibody targeting NTRK3. Anti-NTRK3 Monoclonal Antibody (5D775) can be used in IHC. |
| Synonyms | TRKC, gp145(trkC) |
| Ig Type | IgG1 |
| Clone | 5D775 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells. |
| Antigen Species | Human |
| Gene Name | NTRK3 |
| Gene ID | |
| Protein Name | NT-3 growth factor receptor |
| Uniprot ID |
| Molecular Weight | Theoretical: 94 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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