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Synonyms: NRCAM
Anti-NRCAM Monoclonal Antibody
(6C280)

| Description | Anti-NRCAM Monoclonal Antibody (6C280) is a Mouse antibody targeting NRCAM. Anti-NRCAM Monoclonal Antibody (6C280) can be used in IF. |
| Synonyms | NRCAM |
| Ig Type | IgG1 |
| Clone | 6C280 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/50-1/200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human NRCAM (AA: 1192-1255) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | NRCAM |
| Gene ID | |
| Protein Name | Neuronal cell adhesion molecule |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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