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Synonyms: SXR, SAR, PXR, PRR, PARq, PAR2, PAR1, PAR, ONR1, BXR
Anti-NR1I2 Monoclonal Antibody
(1I770)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
| Description | Anti-NR1I2 Monoclonal Antibody (1I770) is a Mouse antibody targeting NR1I2. Anti-NR1I2 Monoclonal Antibody (1I770) can be used in IF,FCM. |
| Synonyms | SXR, SAR, PXR, PRR, PARq, PAR2, PAR1, PAR, ONR1, BXR |
| Ig Type | IgG2b |
| Clone | 1I770 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human NR1I2 (AA: 1-142) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | NR1I2 |
| Gene ID | |
| Protein Name | Nuclear receptor subfamily 1 group I member 2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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