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Anti-NR1H2 Monoclonal Antibody (5R854)
(Synonyms: UNR, RIP15, NER-I, NER, LXR-b, LXRB) Copy Product Info
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Synonyms: UNR, RIP15, NER-I, NER, LXR-b, LXRB
Catalog No. TMAT-1130 Copy Product Info
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Anti-NR1H2 Monoclonal Antibody (5R854) is a Mouse antibody targeting NR1H2. Anti-NR1H2 Monoclonal Antibody (5R854) can be used in IF,FCM.
Anti-NR1H2 Monoclonal Antibody
(5R854)
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Product Introduction
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Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-NR1H2 Monoclonal Antibody (5R854) is a Mouse antibody targeting NR1H2. Anti-NR1H2 Monoclonal Antibody (5R854) can be used in IF,FCM. |
| Synonyms | UNR, RIP15, NER-I, NER, LXR-b, LXRB |
| Ig Type | IgG2b |
| Clone | 5R854 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]). |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human NR1H2 (AA:1-200) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | NR1H2 |
| Gene ID | |
| Protein Name | Oxysterols receptor LXR-beta |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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