Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-NPC1 Monoclonal Antibody (4B880)
(Synonyms: NPC) Copy Product Info
🥰Excellent
Synonyms: NPC
Catalog No. TMAT-0560 Copy Product Info
🥰Excellent
Anti-NPC1 Monoclonal Antibody (4B880) is a Mouse antibody targeting NPC1. Anti-NPC1 Monoclonal Antibody (4B880) can be used in IHC,FCM.
Anti-NPC1 Monoclonal Antibody
(4B880)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-NPC1 Monoclonal Antibody (4B880) is a Mouse antibody targeting NPC1. Anti-NPC1 Monoclonal Antibody (4B880) can be used in IHC,FCM. |
| Synonyms | NPC |
| Ig Type | IgG1 |
| Clone | 4B880 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human NPC1 (AA: 34-174) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | NPC1 |
| Gene ID | |
| Protein Name | NPC intracellular cholesterol transporter 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags:
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.