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Synonyms: NME1, NM23-H1, NM23, NDPK-A, NDPKA, NBS, NB, GAAD, AWD
Anti-NME1 Monoclonal Antibody
(1K977)

| Description | Anti-NME1 Monoclonal Antibody (1K977) is a Mouse antibody targeting NME1. Anti-NME1 Monoclonal Antibody (1K977) can be used in IHC,IF,FCM. |
| Synonyms | NME1, NM23-H1, NM23, NDPK-A, NDPKA, NBS, NB, GAAD, AWD |
| Ig Type | IgG1 |
| Clone | 1K977 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | non-metastatic cells 1,protein,with a nm23 nucleoside diphosphate kinase gene family,involved in the phosphorylation of nucleoside diphosphates,with a reduced expression in tumor progression to the metastatic phenotype,mutated in agressive neuroblastoma,expressed in lung carcinoma cell lines not in normal lung,pyrimidine biosynthetic pathway. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. Has tumor metastasis-suppressive capacity.Tissue specificity: Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human NME1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | NME1 |
| Gene ID | |
| Protein Name | Nucleoside diphosphate kinase A |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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