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Anti-NKX3.1 Antibody (7T156) is a Mouse antibody targeting NKX3.1. Anti-NKX3.1 Antibody (7T156) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-NKX3.1 Antibody (7T156) is a Mouse antibody targeting NKX3.1. Anti-NKX3.1 Antibody (7T156) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG1, k |
| Clone | 7T156 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Highly expressed in the prostate and, at a lower level, in the testis. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012] |
| Immunogen | KLH conjugated synthetic peptide: human Nkx3.1 |
| Antigen Species | Human |
| Gene Name | NKX3-1 |
| Gene ID | |
| Protein Name | Homeobox protein Nkx-3.1 |
| Uniprot ID | |
| Function | Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. |
| Molecular Weight | Theoretical: 26 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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