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Anti-Nestin Antibody (6Y635)
😃Good
Catalog No. TMAB-09359
Anti-Nestin Antibody (6Y635) is a Mouse antibody targeting Nestin. Anti-Nestin Antibody (6Y635) can be used in IHC-P,WB,IHC-Fr,IF.
Anti-Nestin Antibody (6Y635)
Anti-Nestin Antibody (6Y635)
😃Good
Catalog No. TMAB-09359
Anti-Nestin Antibody (6Y635) is a Mouse antibody targeting Nestin. Anti-Nestin Antibody (6Y635) can be used in IHC-P,WB,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Nestin Antibody (6Y635) is a Mouse antibody targeting Nestin. Anti-Nestin Antibody (6Y635) can be used in IHC-P,WB,IHC-Fr,IF. |
| Ig Type | IgG2a, κ |
| Clone | 6Y635 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; WB: 1:500-1000; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | cytoplasm |
| Tissue Specificity | CNS stem cells. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | PBS, Glycerol, BSA. |
| Concentration | 1mg/ml |
| Research Background | Nestin is a Class VI intermediate filament expressed in the developing central nervous system (CNS) in early embryonic neuroepithelial stem cells. This protein has been widely used as a predominant marker for stem / progenitor cells, glioma cells, and tumor endothelial cells in the mammalian CNS. Furthermore, it is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumor. |
| Immunogen | KLH conjugated synthetic peptide: human Nestin |
| Antigen Species | Human |
| Gene Name | NES |
| Gene ID | |
| Protein Name | Nestin |
| Uniprot ID | |
| Function | Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. |
| Molecular Weight | Theoretical: 178 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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