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Anti-NEFL Monoclonal Antibody (4M590)

(Synonyms: NF-L, NFL, NF68, CMT2E, CMT1F) Copy Product Info
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Synonyms: NF-L, NFL, NF68, CMT2E, CMT1F

Catalog No. TMAT-0727 Copy Product Info
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Anti-NEFL Monoclonal Antibody (4M590) is a Mouse antibody targeting NEFL. Anti-NEFL Monoclonal Antibody (4M590) can be used in WB,IHC,IF,FCM.

Anti-NEFL Monoclonal Antibody
(4M590)

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Product Introduction

Bioactivity
Description
Anti-NEFL Monoclonal Antibody (4M590) is a Mouse antibody targeting NEFL. Anti-NEFL Monoclonal Antibody (4M590) can be used in WB,IHC,IF,FCM.
SynonymsNF-L, NFL, NF68, CMT2E, CMT1F
Ig Type
IgG1
Clone
4M590
Reactivity
Human
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human NEFL expressed in E. Coli.
Antigen Species
Human
Gene Name
NEFL
Gene ID
Protein Name
Neurofilament light polypeptide
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 62 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-NEFL Monoclonal Antibody (4M590) molecular weight