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Synonyms: NF-L, NFL, NF68, CMT2E, CMT1F
Anti-NEFL Monoclonal Antibody
(4M590)

| Description | Anti-NEFL Monoclonal Antibody (4M590) is a Mouse antibody targeting NEFL. Anti-NEFL Monoclonal Antibody (4M590) can be used in WB,IHC,IF,FCM. |
| Synonyms | NF-L, NFL, NF68, CMT2E, CMT1F |
| Ig Type | IgG1 |
| Clone | 4M590 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human NEFL expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | NEFL |
| Gene ID | |
| Protein Name | Neurofilament light polypeptide |
| Uniprot ID |
| Molecular Weight | Theoretical: 62 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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