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Anti-MYL3 Monoclonal Antibody (2V387)

(Synonyms: VLC1, MLC1V, MLC1SB, CMH8) Copy Product Info
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Synonyms: VLC1, MLC1V, MLC1SB, CMH8

Catalog No. TMAT-0763 Copy Product Info
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Anti-MYL3 Monoclonal Antibody (2V387) is a Mouse antibody targeting MYL3. Anti-MYL3 Monoclonal Antibody (2V387) can be used in WB,IHC.

Anti-MYL3 Monoclonal Antibody
(2V387)

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Product Introduction

Bioactivity
Description
Anti-MYL3 Monoclonal Antibody (2V387) is a Mouse antibody targeting MYL3. Anti-MYL3 Monoclonal Antibody (2V387) can be used in WB,IHC.
SynonymsVLC1, MLC1V, MLC1SB, CMH8
Ig Type
IgG1
Clone
2V387
Reactivity
Human
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide.
Concentration1 mg/mL
Research BackgroundMyosins are a large superfamily of motor proteins that move along actin filaments, while hydrolyzing ATP. Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains and four light chains. Activation of smooth and cardiac muscle primarily involves pathways which increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Human myosin light chain has clinical application as a cardiac marker. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of MYL3 expressed in E. Coli.
Antigen Species
Human
Gene Name
MYL3
Gene ID
Protein Name
Myosin light chain 3
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 22 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-MYL3 Monoclonal Antibody (2V387) molecular weight