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Synonyms: SMRP, MPF
Anti-MSLN Monoclonal Antibody
(8M73)

| Description | Anti-MSLN Monoclonal Antibody (8M73) is a Mouse antibody targeting MSLN. Anti-MSLN Monoclonal Antibody (8M73) can be used in WB,FCM. |
| Synonyms | SMRP, MPF |
| Ig Type | IgG2b |
| Clone | 8M73 |
| Reactivity | Human,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MSLN (AA: 37-286) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MSLN |
| Gene ID | |
| Protein Name | Mesothelin |
| Uniprot ID |
| Molecular Weight | Theoretical: 69 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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