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Synonyms: HLALS
Anti-MR1 Monoclonal Antibody
(2I177)

| Description | Anti-MR1 Monoclonal Antibody (2I177) is a Mouse antibody targeting MR1. Anti-MR1 Monoclonal Antibody (2I177) can be used in IHC,IF,FCM. |
| Synonyms | HLALS |
| Ig Type | IgG2a |
| Clone | 2I177 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MR1 (AA: extra(23-302)) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MR1 |
| Gene ID | |
| Protein Name | Major histocompatibility complex class I-related protein 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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