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Anti-mouse CD16/32 Antibody (2E720)
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Catalog No. TMAB-08950
Anti-mouse CD16/32 Antibody (2E720) is a Rat antibody targeting mouse CD16/32. Anti-mouse CD16/32 Antibody (2E720) can be used in FCM.
Anti-mouse CD16/32 Antibody (2E720)
Anti-mouse CD16/32 Antibody (2E720)
😃Good
Catalog No. TMAB-08950
Anti-mouse CD16/32 Antibody (2E720) is a Rat antibody targeting mouse CD16/32. Anti-mouse CD16/32 Antibody (2E720) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $354 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-mouse CD16/32 Antibody (2E720) is a Rat antibody targeting mouse CD16/32. Anti-mouse CD16/32 Antibody (2E720) can be used in FCM. |
| Ig Type | Rat IgG2a, k |
| Clone | 2E720 |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rat |
| Subcellular Localization | Cell membrane. Secreted. Exists also as a soluble receptor. |
| Tissue Specificity | Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4). |
| Research Background | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020] |
| Gene Name | FCGR3A |
| Gene ID | |
| Protein Name | Low affinity immunoglobulin gamma Fc region receptor III-A |
| Function | Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
| Molecular Weight | Theoretical: 27 kDa. Actual: 50-65 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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