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Anti-MMP2 Monoclonal Antibody (5G783)
(Synonyms: TBE-1, MONA, MMP-II, MMP-2, CLG4A, CLG4) Copy Product Info
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Synonyms: TBE-1, MONA, MMP-II, MMP-2, CLG4A, CLG4
Catalog No. TMAT-0757 Copy Product Info
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Anti-MMP2 Monoclonal Antibody (5G783) is a Mouse antibody targeting MMP2. Anti-MMP2 Monoclonal Antibody (5G783) can be used in WB,FCM.
Anti-MMP2 Monoclonal Antibody
(5G783)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-MMP2 Monoclonal Antibody (5G783) is a Mouse antibody targeting MMP2. Anti-MMP2 Monoclonal Antibody (5G783) can be used in WB,FCM. |
| Synonyms | TBE-1, MONA, MMP-II, MMP-2, CLG4A, CLG4 |
| Ig Type | IgG1 |
| Clone | 5G783 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MMP2 (AA: 9-140) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MMP2 |
| Gene ID | |
| Protein Name | 72 kDa type IV collagenase |
| Uniprot ID |
| Molecular Weight | Theoretical: 73.8 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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