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Anti-MET Monoclonal Antibody (6D311)
(Synonyms: RCCP2, HGFR, DFNB97, c-Met, AUTS9) Copy Product Info
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Synonyms: RCCP2, HGFR, DFNB97, c-Met, AUTS9
Catalog No. TMAT-0762 Copy Product Info
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Anti-MET Monoclonal Antibody (6D311) is a Mouse antibody targeting MET. Anti-MET Monoclonal Antibody (6D311) can be used in WB,IHC,IF,FCM.
Anti-MET Monoclonal Antibody
(6D311)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-MET Monoclonal Antibody (6D311) is a Mouse antibody targeting MET. Anti-MET Monoclonal Antibody (6D311) can be used in WB,IHC,IF,FCM. |
| Synonyms | RCCP2, HGFR, DFNB97, c-Met, AUTS9 |
| Ig Type | IgG1 |
| Clone | 6D311 |
| Reactivity | Human,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MET (AA: 743-932) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MET |
| Gene ID | |
| Protein Name | Hepatocyte growth factor receptor |
| Uniprot ID |
| Molecular Weight | Theoretical: 155 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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