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Anti-MDM2 Monoclonal Antibody (5R772)
(Synonyms: LSKB, HDMX, hdm2, ACTFS) Copy Product Info
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Synonyms: LSKB, HDMX, hdm2, ACTFS
Catalog No. TMAT-1186 Copy Product Info
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Anti-MDM2 Monoclonal Antibody (5R772) is a Mouse antibody targeting MDM2. Anti-MDM2 Monoclonal Antibody (5R772) can be used in IHC,FCM.
Anti-MDM2 Monoclonal Antibody
(5R772)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-MDM2 Monoclonal Antibody (5R772) is a Mouse antibody targeting MDM2. Anti-MDM2 Monoclonal Antibody (5R772) can be used in IHC,FCM. |
| Synonyms | LSKB, HDMX, hdm2, ACTFS |
| Ig Type | IgG2b |
| Clone | 5R772 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MDM2 (AA: 26-169) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MDM2 |
| Gene ID | |
| Protein Name | E3 ubiquitin-protein ligase Mdm2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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