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Synonyms: RLFB, P1-MCM3, P1.h, HCC5
Anti-MCM3 Monoclonal Antibody
(6U216)

| Description | Anti-MCM3 Monoclonal Antibody (6U216) is a Mouse antibody targeting MCM3. Anti-MCM3 Monoclonal Antibody (6U216) can be used in WB,IHC,IF,FCM. |
| Synonyms | RLFB, P1-MCM3, P1.h, HCC5 |
| Ig Type | IgG1 |
| Clone | 6U216 |
| Reactivity | Human,Rat,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MCM3 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MCM3 |
| Gene ID | |
| Protein Name | DNA replication licensing factor MCM3 |
| Uniprot ID |
| Molecular Weight | Theoretical: 91 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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