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Anti-MAPK8 Monoclonal Antibody (7N296)
(Synonyms: SAPK1c, SAPK1, PRKM8, JNK-46, JNK21B1/2, JNK1A2, JNK1, JNK) Copy Product Info
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Synonyms: SAPK1c, SAPK1, PRKM8, JNK-46, JNK21B1/2, JNK1A2, JNK1, JNK
Catalog No. TMAT-1055 Copy Product Info
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Anti-MAPK8 Monoclonal Antibody (7N296) is a Mouse antibody targeting MAPK8. Anti-MAPK8 Monoclonal Antibody (7N296) can be used in WB,FCM.
Anti-MAPK8 Monoclonal Antibody
(7N296)
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| Description | Anti-MAPK8 Monoclonal Antibody (7N296) is a Mouse antibody targeting MAPK8. Anti-MAPK8 Monoclonal Antibody (7N296) can be used in WB,FCM. |
| Synonyms | SAPK1c, SAPK1, PRKM8, JNK-46, JNK21B1/2, JNK1A2, JNK1, JNK |
| Ig Type | IgG1 |
| Clone | 7N296 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MAPK8 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MAPK8 |
| Gene ID | |
| Protein Name | Mitogen-activated protein kinase 8 |
| Uniprot ID |
| Molecular Weight | Theoretical: 48.3 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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