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Synonyms: PRKM7, ERK5, ERK4, BMK1
Anti-MAPK7 Monoclonal Antibody
(8E258)

| Description | Anti-MAPK7 Monoclonal Antibody (8E258) is a Mouse antibody targeting MAPK7. Anti-MAPK7 Monoclonal Antibody (8E258) can be used in IHC. |
| Synonyms | PRKM7, ERK5, ERK4, BMK1 |
| Ig Type | IgG1 |
| Clone | 8E258 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MAPK7 (AA: 411-556) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MAPK7 |
| Gene ID | |
| Protein Name | Mitogen-activated protein kinase 7 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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