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Synonyms: PRKMK5, MEK5, MAPKK5, HsT17454
Anti-MAP2K5 Monoclonal Antibody
(5N440)

| Description | Anti-MAP2K5 Monoclonal Antibody (5N440) is a Mouse antibody targeting MAP2K5. Anti-MAP2K5 Monoclonal Antibody (5N440) can be used in WB,IHC,FCM. |
| Synonyms | PRKMK5, MEK5, MAPKK5, HsT17454 |
| Ig Type | IgG1 |
| Clone | 5N440 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MAP2K5 (AA: 63-180) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MAP2K5 |
| Gene ID | |
| Protein Name | Dual specificity mitogen-activated protein kinase kinase 5 |
| Uniprot ID |
| Molecular Weight | Theoretical: 50 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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