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Anti-MAP2K4 Monoclonal Antibody (7E475)
(Synonyms: SERK1, SEK1, PRKMK4, MKK4, MEK4, MAPKK4, MAP2K4, JNKK1, JNKK) Copy Product Info
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Synonyms: SERK1, SEK1, PRKMK4, MKK4, MEK4, MAPKK4, MAP2K4, JNKK1, JNKK
Catalog No. TMAT-1057 Copy Product Info
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Anti-MAP2K4 Monoclonal Antibody (7E475) is a Mouse antibody targeting MAP2K4. Anti-MAP2K4 Monoclonal Antibody (7E475) can be used in WB,IHC,FCM.
Anti-MAP2K4 Monoclonal Antibody
(7E475)
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| Description | Anti-MAP2K4 Monoclonal Antibody (7E475) is a Mouse antibody targeting MAP2K4. Anti-MAP2K4 Monoclonal Antibody (7E475) can be used in WB,IHC,FCM. |
| Synonyms | SERK1, SEK1, PRKMK4, MKK4, MEK4, MAPKK4, MAP2K4, JNKK1, JNKK |
| Ig Type | IgG1 |
| Clone | 7E475 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.Tissue specificity: Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues . |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MAP2K4 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MAP2K4 |
| Gene ID | |
| Protein Name | Dual specificity mitogen-activated protein kinase kinase 4 |
| Uniprot ID |
| Molecular Weight | Theoretical: 42 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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