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Anti-MAP2K2 Monoclonal Antibody (8E150)
(Synonyms: MKK2, MEK2, MAPKK2) Copy Product Info
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Synonyms: MKK2, MEK2, MAPKK2
Catalog No. TMAT-1000 Copy Product Info
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Anti-MAP2K2 Monoclonal Antibody (8E150) is a Mouse antibody targeting MAP2K2. Anti-MAP2K2 Monoclonal Antibody (8E150) can be used in WB,IF,FCM.
Anti-MAP2K2 Monoclonal Antibody
(8E150)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-MAP2K2 Monoclonal Antibody (8E150) is a Mouse antibody targeting MAP2K2. Anti-MAP2K2 Monoclonal Antibody (8E150) can be used in WB,IF,FCM. |
| Synonyms | MKK2, MEK2, MAPKK2 |
| Ig Type | IgG1 |
| Clone | 8E150 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | MAP2K2, also called MEK2, it is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MAP2K2 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MAP2K2 |
| Gene ID | |
| Protein Name | Dual specificity mitogen-activated protein kinase kinase 2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 44 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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