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Anti-LRP6 Monoclonal Antibody (8Z911)

(Synonyms: STHAG7, ADCAD2) Copy Product Info
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Synonyms: STHAG7, ADCAD2

Catalog No. TMAT-0545 Copy Product Info
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Anti-LRP6 Monoclonal Antibody (8Z911) is a Mouse antibody targeting LRP6. Anti-LRP6 Monoclonal Antibody (8Z911) can be used in FCM.

Anti-LRP6 Monoclonal Antibody
(8Z911)

Pack SizePriceUSA StockGlobal StockQuantity
20 µLInquiry7-10 days7-10 days
50 µLInquiry7-10 days7-10 days
100 µLInquiry7-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-LRP6 Monoclonal Antibody (8Z911) is a Mouse antibody targeting LRP6. Anti-LRP6 Monoclonal Antibody (8Z911) can be used in FCM.
SynonymsSTHAG7, ADCAD2
Ig Type
IgG1
Clone
8Z911
Reactivity
Human
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThis gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human LRP6 (AA: extra 1198-1370) expressed in E. Coli.
Antigen Species
Human
Gene Name
LRP6
Gene ID
Protein Name
Low-density lipoprotein receptor-related protein 6
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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