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Anti-LOXL2 Antibody (1L289)

😃Good
Catalog No. TMAY-01974
Alias lysyl oxidase-like 2, 9430067E15Rik, 4930526G11Rik, 1110004B06Rik

Anti-LOXL2 Antibody (1L289) is a Mouse antibody targeting LOXL2. Anti-LOXL2 Antibody (1L289) can be used in ELISA(Cap).

Anti-LOXL2 Antibody (1L289)

Anti-LOXL2 Antibody (1L289)

😃Good
Catalog No. TMAY-01974Alias lysyl oxidase-like 2, 9430067E15Rik, 4930526G11Rik, 1110004B06Rik
Anti-LOXL2 Antibody (1L289) is a Mouse antibody targeting LOXL2. Anti-LOXL2 Antibody (1L289) can be used in ELISA(Cap).
Pack SizePriceAvailabilityQuantity
20 μL$69 7-10 days
100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Mouse Monoclonal

Application: ELISA(Cap)

Reactivity: Human
Aliaslysyl oxidase-like 2, 9430067E15Rik, 4930526G11Rik, 1110004B06Rik
Ig Type
Mouse IgG1
Clone
1L289
Reactivity
Human
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LOXL2 / Lysyl oxidase-like 2 (rh LOXL2 / Lysyl oxidase-like 2; Q9Y4K0Met1-Gln774). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme activity; and more divergent propeptide regions. LOX family enzyme activities catalyze the final enzymatic conversion required for the formation of normal biosynthetic collagen and elastin cross-links. LOXL2 is expressed by pre-hypertrophic and hypertrophic chondrocytes in vivo, and that LOXL2 expression is regulated in vitro as a function of chondrocyte differentiation. LOXL2 promotes chondrocyte differentiation by mechanisms that are likely to include roles as both a regulator and an effector of chondrocyte differentiation. LOXL2 expression could also be explored as a molecular target in the prevention of breast cancer progression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human LOXL2 / Lysyl oxidase-like 2 Protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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