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Anti-LOXL2 Antibody (1L289) is a Mouse antibody targeting LOXL2. Anti-LOXL2 Antibody (1L289) can be used in ELISA(Cap).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 20 μL | $69 | 7-10 days | 7-10 days | |
| 100 μL | $199 | 7-10 days | 7-10 days |
| Description | Anti-LOXL2 Antibody (1L289) is a Mouse antibody targeting LOXL2. Anti-LOXL2 Antibody (1L289) can be used in ELISA(Cap). |
| Synonyms | lysyl oxidase-like 2, 9430067E15Rik, 4930526G11Rik, 1110004B06Rik |
| Ig Type | Mouse IgG1 |
| Clone | 1L289 |
| Reactivity | Human |
| Specificity | Human LOXL2 |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LOXL2 / Lysyl oxidase-like 2 (rh LOXL2 / Lysyl oxidase-like 2; Q9Y4K0Met1-Gln774). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme activity; and more divergent propeptide regions. LOX family enzyme activities catalyze the final enzymatic conversion required for the formation of normal biosynthetic collagen and elastin cross-links. LOXL2 is expressed by pre-hypertrophic and hypertrophic chondrocytes in vivo, and that LOXL2 expression is regulated in vitro as a function of chondrocyte differentiation. LOXL2 promotes chondrocyte differentiation by mechanisms that are likely to include roles as both a regulator and an effector of chondrocyte differentiation. LOXL2 expression could also be explored as a molecular target in the prevention of breast cancer progression. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human LOXL2 / Lysyl oxidase-like 2 Protein |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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