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Synonyms: PRO1, LMNL1, LMNC, LMN1, LFP, LDP1, IDC, HGPS, FPLD2, FPLD, FPL, EMD2, CMT2B1, CMD1A, CDDC, CDCD1
Anti-LMNA Monoclonal Antibody
(5B815)

| Description | Anti-LMNA Monoclonal Antibody (5B815) is a Mouse antibody targeting LMNA. Anti-LMNA Monoclonal Antibody (5B815) can be used in WB,IHC. |
| Synonyms | PRO1, LMNL1, LMNC, LMN1, LFP, LDP1, IDC, HGPS, FPLD2, FPLD, FPL, EMD2, CMT2B1, CMD1A, CDDC, CDCD1 |
| Ig Type | IgG1 |
| Clone | 5B815 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human LMNA expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | LMNA |
| Gene ID | |
| Protein Name | Prelamin-A/C |
| Uniprot ID |
| Molecular Weight | Theoretical: 74 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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