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Anti-LDLR Monoclonal Antibody (4C80)
(Synonyms: LDLCQ2, FHC, FH) Copy Product Info
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Synonyms: LDLCQ2, FHC, FH
Catalog No. TMAT-0538 Copy Product Info
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Anti-LDLR Monoclonal Antibody (4C80) is a Mouse antibody targeting LDLR. Anti-LDLR Monoclonal Antibody (4C80) can be used in IHC,FCM.
Anti-LDLR Monoclonal Antibody
(4C80)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-LDLR Monoclonal Antibody (4C80) is a Mouse antibody targeting LDLR. Anti-LDLR Monoclonal Antibody (4C80) can be used in IHC,FCM. |
| Synonyms | LDLCQ2, FHC, FH |
| Ig Type | IgG1 |
| Clone | 4C80 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.r |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human LDLR (AA: 22-150) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | LDLR |
| Gene ID | |
| Protein Name | Low-density lipoprotein receptor |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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