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Anti-LCK Monoclonal Antibody (3D619)
(Synonyms: YT16, pp58lck, p56lck, LSK, IMD22) Copy Product Info
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Synonyms: YT16, pp58lck, p56lck, LSK, IMD22
Catalog No. TMAT-0708 Copy Product Info
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Anti-LCK Monoclonal Antibody (3D619) is a Mouse antibody targeting LCK. Anti-LCK Monoclonal Antibody (3D619) can be used in WB.
Anti-LCK Monoclonal Antibody
(3D619)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-LCK Monoclonal Antibody (3D619) is a Mouse antibody targeting LCK. Anti-LCK Monoclonal Antibody (3D619) can be used in WB. |
| Synonyms | YT16, pp58lck, p56lck, LSK, IMD22 |
| Ig Type | IgG2a |
| Clone | 3D619 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Lck (lymphocyte-specific protein tyrosine kinase), with 509-amino acid protein (about 56kDa), belongs to the Src non-receptor tyrosine kinases family. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Lck is expressed predominantly in T cells and is localized to the inner surface of the plasma membrane. Lck is activated after T cell stimulation and is required for T-cell proliferation and IL-2 production. Aberrant expression or activation of Lck kinase has been reported in both lymphoid and nonlymphoid malignancies. In addition, inhibition of Lck has been a target to prevent lymphocyte activation and acute rejection. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human Lck expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | LCK |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase Lck |
| Uniprot ID |
| Molecular Weight | Theoretical: 56 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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