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Anti-Latexin Antibody (7N890) (Synonyms: latexin)
Catalog No. TMAY-00472 Copy Product Info
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Anti-Latexin Antibody (7N890) is a Mouse antibody targeting Latexin. Anti-Latexin Antibody (7N890) can be used in ELISA,IP,WB.
Anti-Latexin Antibody (7N890)
Copy Product Info🥰Excellent
Catalog No. TMAY-00472
Synonyms latexin
Anti-Latexin Antibody (7N890) is a Mouse antibody targeting Latexin. Anti-Latexin Antibody (7N890) can be used in ELISA,IP,WB.
Anti-Latexin Antibody
(7N890)
(7N890)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Latexin Antibody (7N890) is a Mouse antibody targeting Latexin. Anti-Latexin Antibody (7N890) can be used in ELISA,IP,WB. |
| Synonyms | latexin |
| Ig Type | Mouse IgG1 |
| Clone | 7N890 |
| Reactivity | Human |
| Specificity | Human Latexin No cross-reactivity in ELISA with E.coli lysate |
| Verified Activity | 1. Anti-LXN mouse monoclonal antibody at 1:500 dilution. -Lane A: A549 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:26 kDa. -Observed band size:26 kDa. 2. LXN was immunoprecipitated using: -Lane A:0.5 mg MCF-7 Whole Cell Lysate -0.5 µL anti-LXN mouse monoclonal antibody and 15 μl of 50 % Protein G agarose. -Primary antibody: -Anti-LXN mouse monoclonal antibody, at 1:500 dilution. -Secondary antibody: -Dylight 800-labeled antibody to Mouse IgG (H+L), at 1:7500 dilution. -Developed using the odyssey technique. -Performed under reducing conditions. -Predicted band size: 25.7 kDa. -Observed band size: 27 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1:1000; ELISA: 1:5000-1:10000; IP: 1-2 μL/mg of lysate |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Latexin (rh Latexin; TMPY-00870; NP_064554.3; Glu 2-Glu 222). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in the heart, prostate, ovary, kidney, pancreas, and colon. Latexin / LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional specification of the neocortex in development in rats. The 222 amino acid latexin in the human shows different expression distribution with high levels in heart, prostate, ovary, kidney, pancreas, and colon, but only moderate or low levels in other tissues including the brain. Latexin is also expressed at high levels and is inducible in macrophages in concert with other protease inhibitors and potential protease targets, and thus is suggested to play a role in inflammation and innate immunity pathways. Despite the non-detectable sequence similarity with plant and parasite inhibitors, Latexin is related to a human putative tumor suppressor protein, TIG1. Also, Latexin is implicated in Alzheimer's disease. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Latexin protein (TMPY-00870) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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