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Anti-Latexin Antibody (1T982)

😃Good
Catalog No. TMAY-03061
Alias latexin

Anti-Latexin Antibody (1T982) is a Rabbit antibody targeting Latexin. Anti-Latexin Antibody (1T982) can be used in ELISA.

Anti-Latexin Antibody (1T982)

Anti-Latexin Antibody (1T982)

😃Good
Catalog No. TMAY-03061Alias latexin
Anti-Latexin Antibody (1T982) is a Rabbit antibody targeting Latexin. Anti-Latexin Antibody (1T982) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Latexin Antibody (1T982) is a Rabbit antibody targeting Latexin. Anti-Latexin Antibody (1T982) can be used in ELISA.
Aliaslatexin
Ig Type
Monoclonal Rabbit IgG
Clone
1T982
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse Latexin / LXN (rM Latexin / LXN; TMPY-01771; NP_058033.2; Glu 2-Glu 222).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLatexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in the heart, prostate, ovary, kidney, pancreas, and colon. Latexin / LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional specification of the neocortex in development in rats. The 222 amino acid latexin in the human shows different expression distribution with high levels in heart, prostate, ovary, kidney, pancreas, and colon, but only moderate or low levels in other tissues including the brain. Latexin is also expressed at high levels and is inducible in macrophages in concert with other protease inhibitors and potential protease targets, and thus is suggested to play a role in inflammation and innate immunity pathways. Despite the non-detectable sequence similarity with plant and parasite inhibitors, Latexin is related to a human putative tumor suppressor protein, TIG1. Also, Latexin is implicated in Alzheimer's disease.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse Latexin / LXN protein (TMPY-01771)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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