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Anti-KRT7 Antibody (7Y543) is a Rabbit antibody targeting KRT7. Anti-KRT7 Antibody (7Y543) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $270 | 7-10 days |
Description | Anti-KRT7 Antibody (7Y543) is a Rabbit antibody targeting KRT7. Anti-KRT7 Antibody (7Y543) can be used in WB. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7Y543 |
Reactivity | Human |
Verified Activity | Anti-KRT7 rabbit monoclonal antibody at 1:10000 dilution. -Lane A: Hela Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:51 kDa. -Observed band size:55 kDa |
Application | WB |
Recommended Dose | WB: 1:2000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human Cytokeratin 7/KRT7. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | KRT7 (Keratin 7) is a Protein Coding gene. The protein encoded by this gene is a member of the keratin gene family. One AS, designated Homo sapiens keratin 7 (KRT7-AS), was selected due to its marked upregulation and concordant expression with its cognate sense counterpart, KRT7, in GC tissues and cell lines. KRT7-AS formed an RNA-RNA hybrid with KRT7 and controlled KRT7 expression at both the mRNA and the post-transcriptional levels. Moreover, forced overexpression of the KRT7-overlapping region (OL) of KRT7-AS (but not its non-KRT7-OL portions) increased keratin 7 protein levels in cells. Finally, forced overexpression of full-length KRT7-AS or OL KRT7-AS (but not its non-KRT7-OL regions) promoted GC cell proliferation and migration. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide corresponding to the center region of the Human Cytokeratin 7/KRT7 |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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