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Anti-KRT6A Monoclonal Antibody (1E392)
(Synonyms: PC3, KRT6D, KRT6C, KRT6A, K6D, K6C, K6A, CK-6E, CK6D, CK-6C, CK6C) Copy Product Info
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Synonyms: PC3, KRT6D, KRT6C, KRT6A, K6D, K6C, K6A, CK-6E, CK6D, CK-6C, CK6C
Catalog No. TMAT-0658 Copy Product Info
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Anti-KRT6A Monoclonal Antibody (1E392) is a Mouse antibody targeting KRT6A. Anti-KRT6A Monoclonal Antibody (1E392) can be used in WB,IF,FCM.
Anti-KRT6A Monoclonal Antibody
(1E392)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-KRT6A Monoclonal Antibody (1E392) is a Mouse antibody targeting KRT6A. Anti-KRT6A Monoclonal Antibody (1E392) can be used in WB,IF,FCM. |
| Synonyms | PC3, KRT6D, KRT6C, KRT6A, K6D, K6C, K6A, CK-6E, CK6D, CK-6C, CK6C |
| Ig Type | IgG2b |
| Clone | 1E392 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human KRT6A (AA: 253-352) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | KRT6A |
| Gene ID | |
| Protein Name | Keratin, type II cytoskeletal 6A |
| Uniprot ID |
| Molecular Weight | Theoretical: 60 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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