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Synonyms: KRT1, K1CO, K15, CK15
Anti-KRT15 Monoclonal Antibody
(3I568)

| Description | Anti-KRT15 Monoclonal Antibody (3I568) is a Mouse antibody targeting KRT15. Anti-KRT15 Monoclonal Antibody (3I568) can be used in WB,IHC,IF,FCM. |
| Synonyms | KRT1, K1CO, K15, CK15 |
| Ig Type | IgG2a |
| Clone | 3I568 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of KRT15 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | KRT15 |
| Gene ID | |
| Protein Name | Keratin, type I cytoskeletal 15 |
| Uniprot ID |
| Molecular Weight | Theoretical: 49 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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