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Anti-KLHL13 Monoclonal Antibody (6V321)
(Synonyms: MGC74791, KLHL13, FLJ10262, BKLHD2) Copy Product Info
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Synonyms: MGC74791, KLHL13, FLJ10262, BKLHD2
Catalog No. TMAT-1600 Copy Product Info
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Anti-KLHL13 Monoclonal Antibody (6V321) is a Mouse antibody targeting KLHL13. Anti-KLHL13 Monoclonal Antibody (6V321) can be used in WB,IHC,IF,FCM.
Anti-KLHL13 Monoclonal Antibody
(6V321)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-KLHL13 Monoclonal Antibody (6V321) is a Mouse antibody targeting KLHL13. Anti-KLHL13 Monoclonal Antibody (6V321) can be used in WB,IHC,IF,FCM. |
| Synonyms | MGC74791, KLHL13, FLJ10262, BKLHD2 |
| Ig Type | IgG1 |
| Clone | 6V321 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | KLHL13 (kelch-like 13), also known as BKLHD2 (BTB and kelch domain-containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate- specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Via its BTB and C-terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL-3 ligase. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human KLHL13 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | KLHL13 |
| Gene ID | |
| Protein Name | Kelch-like protein 13 |
| Uniprot ID |
| Molecular Weight | Theoretical: 74 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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