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Anti-KIT Monoclonal Antibody (4K230)
(Synonyms: SCFR, PBT, C-Kit, CD117) Copy Product Info
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Synonyms: SCFR, PBT, C-Kit, CD117
Catalog No. TMAT-0799 Copy Product Info
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Anti-KIT Monoclonal Antibody (4K230) is a Mouse antibody targeting KIT. Anti-KIT Monoclonal Antibody (4K230) can be used in WB,IHC.
Anti-KIT Monoclonal Antibody
(4K230)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-KIT Monoclonal Antibody (4K230) is a Mouse antibody targeting KIT. Anti-KIT Monoclonal Antibody (4K230) can be used in WB,IHC. |
| Synonyms | SCFR, PBT, C-Kit, CD117 |
| Ig Type | IgG1 |
| Clone | 4K230 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell prolif- eration, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto- oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human KIT expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | KIT |
| Gene ID | |
| Protein Name | Mast/stem cell growth factor receptor Kit |
| Uniprot ID |
| Molecular Weight | Theoretical: 145 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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