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Anti-KI67 Monoclonal Antibody (8A973)

(Synonyms: MKI67, KIA, Ki-67) Copy Product Info
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Synonyms: MKI67, KIA, Ki-67

Catalog No. TMAT-1058 Copy Product Info
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Anti-KI67 Monoclonal Antibody (8A973) is a Mouse antibody targeting KI67. Anti-KI67 Monoclonal Antibody (8A973) can be used in IHC,IF.

Anti-KI67 Monoclonal Antibody
(8A973)

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Product Introduction

Bioactivity
Description
Anti-KI67 Monoclonal Antibody (8A973) is a Mouse antibody targeting KI67. Anti-KI67 Monoclonal Antibody (8A973) can be used in IHC,IF.
SynonymsMKI67, KIA, Ki-67
Ig Type
IgG2b
Clone
8A973
Reactivity
Human,Mouse,Rat,Rabbit,Monkey
Application
Recommended Dose
IHC: 1/100-1/500; IF: 1/50-1/500
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide.
Concentration1 mg/mL
Research BackgroundKi67, also known as MKI67, it is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH.
Antigen Species
Human
Gene Name
MKI67
Gene ID
Protein Name
Proliferation marker protein Ki-67
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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