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Synonyms: TSGA, KIAA0742, KDM3A, JMJD1A, JMJD1, JHMD2A, JHDM2A, DKFZp686P07111, DKFZp686A24246
Anti-KDM3A Monoclonal Antibody
(3S36)

| Description | Anti-KDM3A Monoclonal Antibody (3S36) is a Mouse antibody targeting KDM3A. Anti-KDM3A Monoclonal Antibody (3S36) can be used in WB,IHC. |
| Synonyms | TSGA, KIAA0742, KDM3A, JMJD1A, JMJD1, JHMD2A, JHDM2A, DKFZp686P07111, DKFZp686A24246 |
| Ig Type | IgG1 |
| Clone | 3S36 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. JMJD1A functions as a mono- and dimethylation-specific demethylase, binding iron and -ketoglutarate as cofactors and demethylating Lysine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human KDM3A expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | KDM3A |
| Gene ID | |
| Protein Name | Lysine-specific demethylase 3A |
| Uniprot ID |
| Molecular Weight | Theoretical: 147 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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