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Anti-KCND2 Monoclonal Antibody (8O389)

(Synonyms: RK5, KV4.2) Copy Product Info
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Synonyms: RK5, KV4.2

Catalog No. TMAT-1598 Copy Product Info
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Anti-KCND2 Monoclonal Antibody (8O389) is a Mouse antibody targeting KCND2. Anti-KCND2 Monoclonal Antibody (8O389) can be used in FCM.

Anti-KCND2 Monoclonal Antibody
(8O389)

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Product Introduction

Bioactivity
Description
Anti-KCND2 Monoclonal Antibody (8O389) is a Mouse antibody targeting KCND2. Anti-KCND2 Monoclonal Antibody (8O389) can be used in FCM.
SynonymsRK5, KV4.2
Ig Type
IgG1
Clone
8O389
Reactivity
Human
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundVoltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human KCND2 (AA: 27-184) expressed in E. Coli.
Antigen Species
Human
Gene Name
KCND2
Gene ID
Protein Name
A-type voltage-gated potassium channel KCND2
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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