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Anti-JAM3 Monoclonal Antibody (4P627)

(Synonyms: JAM-C, JAMC, JAM-3, JAM-2) Copy Product Info
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Synonyms: JAM-C, JAMC, JAM-3, JAM-2

Catalog No. TMAT-1520 Copy Product Info
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Anti-JAM3 Monoclonal Antibody (4P627) is a Mouse antibody targeting JAM3. Anti-JAM3 Monoclonal Antibody (4P627) can be used in WB,FCM.

Anti-JAM3 Monoclonal Antibody
(4P627)

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Product Introduction

Bioactivity
Description
Anti-JAM3 Monoclonal Antibody (4P627) is a Mouse antibody targeting JAM3. Anti-JAM3 Monoclonal Antibody (4P627) can be used in WB,FCM.
SynonymsJAM-C, JAMC, JAM-3, JAM-2
Ig Type
IgG1
Clone
4P627
Reactivity
Human
Application
Recommended Dose
WB: 1/500-1/2000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human JAM3 (AA: extra 32-241) expressed in E. Coli.
Antigen Species
Human
Gene Name
JAM3
Gene ID
Protein Name
Junctional adhesion molecule C
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 35 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-JAM3 Monoclonal Antibody (4P627) molecular weight