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Synonyms: JAM-C, JAMC, JAM-3, JAM-2
Anti-JAM3 Monoclonal Antibody
(4P627)

| Description | Anti-JAM3 Monoclonal Antibody (4P627) is a Mouse antibody targeting JAM3. Anti-JAM3 Monoclonal Antibody (4P627) can be used in WB,FCM. |
| Synonyms | JAM-C, JAMC, JAM-3, JAM-2 |
| Ig Type | IgG1 |
| Clone | 4P627 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human JAM3 (AA: extra 32-241) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | JAM3 |
| Gene ID | |
| Protein Name | Junctional adhesion molecule C |
| Uniprot ID |
| Molecular Weight | Theoretical: 35 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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