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Anti-JAM-A Antibody (5G304) is a Mouse antibody targeting JAM-A. Anti-JAM-A Antibody (5G304) can be used in ELISA,ELISA(Det).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $68 | 7-10 days | |
100 μL | $198 | 7-10 days |
Description | Anti-JAM-A Antibody (5G304) is a Mouse antibody targeting JAM-A. Anti-JAM-A Antibody (5G304) can be used in ELISA,ELISA(Det). |
Alias | F11 receptor |
Ig Type | Monoclonal Mouse IgG2a |
Clone | 5G304 |
Reactivity | Human |
Application | ELISA,ELISA(Det) |
Recommended Dose | ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human JAM-A extracellular domain (rh JAM-A; TMPY-01035; Met 1-Ala 242; NP_058642.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer. |
Conjucates | Unconjugated |
Others Formats | HRP |
Antibody Types Available | 2 |
Immunogen | Recombinant Human JAM-A protein (TMPY-01035) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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