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Synonyms: LJAK, JAKL
Anti-JAK3 Monoclonal Antibody
(4J726)

| Description | Anti-JAK3 Monoclonal Antibody (4J726) is a Mouse antibody targeting JAK3. Anti-JAK3 Monoclonal Antibody (4J726) can be used in WB,IF,FCM. |
| Synonyms | LJAK, JAKL |
| Ig Type | IgG1 |
| Clone | 4J726 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human JAK3 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | JAK3 |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase JAK3 |
| Uniprot ID |
| Molecular Weight | Theoretical: 125 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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