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Anti-ITGB4 Monoclonal Antibody (5E613)

(Synonyms: CD104) Copy Product Info
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Synonyms: CD104

Catalog No. TMAT-0861 Copy Product Info
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Anti-ITGB4 Monoclonal Antibody (5E613) is a Mouse antibody targeting ITGB4. Anti-ITGB4 Monoclonal Antibody (5E613) can be used in IHC,FCM.

Anti-ITGB4 Monoclonal Antibody
(5E613)

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Product Introduction

Bioactivity
Description
Anti-ITGB4 Monoclonal Antibody (5E613) is a Mouse antibody targeting ITGB4. Anti-ITGB4 Monoclonal Antibody (5E613) can be used in IHC,FCM.
SynonymsCD104
Ig Type
IgG1
Clone
5E613
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide.
Concentration1 mg/mL
Research BackgroundIntegrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. Coli.
Antigen Species
Human
Gene Name
ITGB4
Gene ID
Protein Name
Integrin beta-4
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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