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Anti-IL7R/CD127 Antibody (2S712)
😃Good
Catalog No. TMAB-07674
Anti-IL7R/CD127 Antibody (2S712) is a Mouse antibody targeting IL7R/CD127. Anti-IL7R/CD127 Antibody (2S712) can be used in IHC-P,IHC-Fr,IF.
Anti-IL7R/CD127 Antibody (2S712)
Anti-IL7R/CD127 Antibody (2S712)
😃Good
Catalog No. TMAB-07674
Anti-IL7R/CD127 Antibody (2S712) is a Mouse antibody targeting IL7R/CD127. Anti-IL7R/CD127 Antibody (2S712) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-IL7R/CD127 Antibody (2S712) is a Mouse antibody targeting IL7R/CD127. Anti-IL7R/CD127 Antibody (2S712) can be used in IHC-P,IHC-Fr,IF. |
| Clone | 2S712 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Secreted and Cell membrane. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). |
| Immunogen | Recombinant Protein: human IL-7R Alpha / CD127 protein |
| Antigen Species | Human |
| Gene Name | IL7R |
| Gene ID | |
| Protein Name | Interleukin-7 receptor subunit alpha |
| Uniprot ID | |
| Function | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
| Molecular Weight | Theoretical: 50 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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